HPV16 E7 Antikörper (AbBy Fluor® 594)

Produktnummer ABIN2814497

Dieser Anti-HPV16 E7 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von HPV16 E7 in WB, IF (p), FACS und IF (cc). Geeignet für Virus.

Kurzübersicht für HPV16 E7 Antikörper (AbBy Fluor® 594) (ABIN2814497)

Target: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Reaktivität: Virus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HPV16 E7 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-HPV16 E7 Antikörper (AbBy Fluor® 594)

Spezifität: This antibody may also detect HPV35-E7

Kreuzreaktivität: Human, Virus

Kreuzreaktivität (Details): HPV16

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from middle of HPV16-E7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HPV16 E7

Target: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Andere Bezeichnung: HPV16-E7

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: Protein E7, E7

Background: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.

Gen-ID: 1489079

UniProt: P03129