HOXA3 Antikörper (AA 201-300) (AbBy Fluor® 594)

Produktnummer ABIN2814457

Der Kaninchen Polyklonal Anti-HOXA3-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, HOXA3 in Proben von Human zu detektieren.

Kurzübersicht für HOXA3 Antikörper (AA 201-300) (AbBy Fluor® 594) (ABIN2814457)

Target: HOXA3 (Homeobox A3 (HOXA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXA3 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-HOXA3 Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 201-300

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOXA3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HOXA3

Target: HOXA3 (Homeobox A3 (HOXA3))

Andere Bezeichnung: HOXA3

Hintergrund:

Synonyms: Homeo box 1E, Homeo box A3, Homeobox 1E, Homeobox A3, Homeobox protein HOX A3, Homeobox protein Hox-1E, Homeobox protein Hox-A3, Homeobox protein HOXA3, Homeobox1E, HomeoboxA3, HOX 1, Hox 1.5 like protein, HOX 1E, HOX A3, HOX1, Hox1.5, Hox1.5 like protein, HOX1E, HOXA 3, HOXA3, HXA3_HUMAN, MGC10155.

Background: The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. HOX genes that occupy the same relative position along the 5? to 3? coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent HOX genes on the same chromosome. HoxA3, in conjunction with Pax1, mediates the development of the thymus, parathyroid gland, and carotid body. Its expression in the third pharyngeal arch and pouch is required for development of the third arch artery, and homozygous null HoxA3 mutants lack the carotid body. HoxA3 also regulates hindbrain development by controlling the axon projection pattern of motor neurons and sensory neurons of the proximal and distal ganglia.