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GC-Rich Promoter Binding Protein 1 (GPBP1) (AA 11-110) Antikörper (Alexa Fluor 594)

GPBP1 Reaktivität: Maus IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 594
Produktnummer ABIN2813939
$470.46
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle GC-Rich Promoter Binding Protein 1 (GPBP1) Antikörper anzeigen
    GC-Rich Promoter Binding Protein 1 (GPBP1)
    Bindungsspezifität
    • 14
    • 3
    • 1
    • 1
    AA 11-110
    Reaktivität
    • 18
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 22
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Alexa Fluor 594
    Applikation
    • 12
    • 12
    • 10
    • 5
    • 4
    • 4
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GPBP1/Vasculin
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    GC-Rich Promoter Binding Protein 1 (GPBP1)
    Andere Bezeichnung
    GPBP1/Vasculin (GPBP1 Produkte)
    Synonyme
    MGC80437 antikoerper, Vasculin antikoerper, DKFZp459A203 antikoerper, GPBP antikoerper, SSH6 antikoerper, VASCULIN antikoerper, 1700034P14Rik antikoerper, AU019836 antikoerper, D230035M11Rik antikoerper, Gpbp antikoerper, mGPBP antikoerper, RGD1305492 antikoerper, GC-rich promoter binding protein 1 L homeolog antikoerper, GC-rich promoter binding protein 1 antikoerper, gpbp1.L antikoerper, gpbp1 antikoerper, GPBP1 antikoerper, Gpbp1 antikoerper
    Hintergrund

    Vascular wall-linked protein, or Vasculin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vasculin gene produces three variants. Vasculin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regulated expression of Vasculin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vasculin as a marker for atherosclerosis.

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: DKFZp761C169, GC rich promoter binding protein 1, GC-rich promoter-binding protein 1, GPBP, Gpbp1, GPBP1_HUMAN, MGC126339, SSH6, Vascular wall linked, Vascular wall-linked protein, Vasculin.

    Gen-ID
    65056
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