COQ10B Antikörper (AA 38-110) (Alexa Fluor 594)

Produktnummer ABIN2811866

Produktdetails anti-COQ10B Antikörper

Target: COQ10B (Coenzyme Q10 Homolog B (COQ10B))

Bindungsspezifität: AA 38-110

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COQ10B Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Spezifität: Cross-reactivity with COQ10A (91 % homology with the immunogen sequence),

Homologie: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COQ10B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu COQ10B

Target: COQ10B (Coenzyme Q10 Homolog B (COQ10B))

Andere Bezeichnung: COQ10B (COQ10B Produkte)

Synonyme: 1500041J02Rik antikoerper, 1700030I21Rik antikoerper, 9530077A17Rik antikoerper, AV002237 antikoerper, AW742641 antikoerper, RGD1359509 antikoerper, fc38f07 antikoerper, im:6912267 antikoerper, wu:fc38f07 antikoerper, zgc:112103 antikoerper, coenzyme Q10B antikoerper, COQ10B antikoerper, Coq10b antikoerper, coq10b antikoerper

Hintergrund:

COQ10B, Coenzyme Q10, is a 247 amino acid protein encoded by the human gene COQ10B. COQ10B is a mitochondrial protein that belongs to the COQ10 family. COQ10B is an essential biological cofactor which increases brain mitochondrial concentration and exerts neuroprotective effects. Plasma COQ10B levels decrease in patients with advanced chronic heart failure (CHF) while COQ10B levels in hyperthyroid patients are found among the lowest detected in human diseases. Likewise, COQ10B is elevated in hypothyroid subjects, also in subclinical conditions, suggesting the usefulness of this index in assessing metabolic status in thyroid disorders. It is believed that secretion of adrenal hormones is in some way related to COQ10B levels, both in augmented and reduced conditions. However, since thyroid hormones have an important role in modulating COQ10B levels and metabolism, when coexistent, thyroid deficiency seems to play a prevalent role in comparison with adrenal deficiency.

Subcellular location: Cytoplasm, Cell membrane

Synonyms: Coenzyme Q10, Coenzyme Q10 B, Coenzyme Q10 homolog B, Coenzyme Q10B, CQ10B_HUMAN.

Gen-ID: 80219

UniProt: Q9H8M1