Calsyntenin 2 Antikörper (AA 261-360) (AbBy Fluor® 594)

Produktnummer ABIN2811753

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Calsyntenin 2 in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Calsyntenin 2 Antikörper (AA 261-360) (AbBy Fluor® 594) (ABIN2811753)

Target: Calsyntenin 2 (CLSTN2)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calsyntenin 2 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Calsyntenin 2 Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 261-360

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLSTN2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Calsyntenin 2

Target: Calsyntenin 2 (CLSTN2)

Andere Bezeichnung: CLSTN2

Hintergrund:

Synonyms: Alc, Alcadein, Alcadein Gamma, Alcagamma, Alzheimer's disease related cadherin like protein, Calsyntenin 2, CLSTN 2, CS 2, CS2, FLJ39113, FLJ39499, MGC119560, CSTN2_HUMAN.

Background: Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.