CCT8L2 Antikörper (AA 509-557) (AbBy Fluor® 594)

Produktnummer ABIN2811582

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CCT8L2 in WB, IF (cc) und IF (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CCT8L2 Antikörper (AA 509-557) (AbBy Fluor® 594) (ABIN2811582)

Target: CCT8L2 (Chaperonin Containing TCP1, Subunit 8 (Theta)-Like 2 (CCT8L2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCT8L2 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CCT8L2 Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 509-557

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CESK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CCT8L2

Target: CCT8L2 (Chaperonin Containing TCP1, Subunit 8 (Theta)-Like 2 (CCT8L2))

Andere Bezeichnung: CESK1

Hintergrund:

Synonyms: CCT8L2, KCNMB3L, T complex protein 1, CESK1, chaperonin containing TCP1, subunit 8 theta-like 2, Putative T-complex protein 1 subunit theta-like 2, T complex protein 1, chaperonin containing TCP1, subunit 8 theta-like 2, TCPQM_HUMAN.

Background: CESK1, also known as CCT8L2 (chaperonin containing TCP1, subunit 8 theta-like 2), is a 557 amino acid protein that localizes to the cytoplasm and is thought to function as a molecular chaperone, possibly assisting protein folding after ATP hydrolysis. CESK1 belongs to the TCP-1 chaperonin family and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias.

Gen-ID: 150160