CACYBP Antikörper (AA 61-95) (AbBy Fluor® 594)

Produktnummer ABIN2811024

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CACYBP in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CACYBP Antikörper (AA 61-95) (AbBy Fluor® 594) (ABIN2811024)

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACYBP Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CACYBP Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 61-95

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CACYBP/S100A6BP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CACYBP

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Andere Bezeichnung: CACYBP/S100A6BP

Hintergrund:

Synonyms: SIAH Interacting Protein, CACYBP, Calcyclin binding protein, GIG 5, GIG5, Growth inhibiting gene 5, Calcyclin-binding protein, Siah-interacting protein, Growth inhibiting gene 5 protein, hCacyBP, MGC87971, PNAS 107, PNAS107, RP1 102G20.6, S100A6 binding protein, S100A6BP, SIP.

Background: CacyBP is a 228 amino acid protein encoded by the human gene CACYBP. CacyBP is primarily a nuclear protein that contains one CS domain and one SGS domain. CacyBP is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of b-catenin. CacyBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on b-catenin protein expression and transcriptional activation of TCF/LEF.

Pathways: Response to Growth Hormone Stimulus