C6ORF57 Antikörper (AA 41-108) (Alexa Fluor 594)

Produktnummer ABIN2810904

Produktdetails anti-C6ORF57 Antikörper

Target: C6ORF57 (Chromosome 6 Open Reading Frame 57 (C6ORF57))

Bindungsspezifität: AA 41-108

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C6ORF57 Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6orf57

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu C6ORF57

Target: C6ORF57 (Chromosome 6 Open Reading Frame 57 (C6ORF57))

Andere Bezeichnung: C6orf57 (C6ORF57 Produkte)

Synonyme: 1700001E18Rik antikoerper, C6orf57 antikoerper, succinate dehydrogenase complex assembly factor 4 antikoerper, SDHAF4 antikoerper, Sdhaf4 antikoerper

Hintergrund:

Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf57 gene product has been provisionally designated C6orf57 pending further characterization.

Subcellular location: Cytoplasm

Synonyms: C6orf57, CF057_HUMAN, Chromosome 6 open reading frame 57, UPF0369 protein C6orf57.

Gen-ID: 135154