METTL24 Antikörper (AA 301-366) (Alexa Fluor 594)

Produktnummer ABIN2810891

Produktdetails anti-METTL24 Antikörper

Target: METTL24 (Methyltransferase Like 24 (METTL24))

Bindungsspezifität: AA 301-366

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser METTL24 Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6orf186

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu METTL24

Target: METTL24 (Methyltransferase Like 24 (METTL24))

Andere Bezeichnung: C6orf186 (METTL24 Produkte)

Synonyme: C6orf186 antikoerper, dJ71D21.2 antikoerper, 9030224M15Rik antikoerper, methyltransferase like 24 antikoerper, METTL24 antikoerper, Mettl24 antikoerper

Hintergrund:

Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf186 gene product has been provisionally designated C6orf186 pending further characterization.

Subcellular location: Secreted

Synonyms: C6orf186, MET24_HUMAN, Chromosome 6 open reading frame 186, dJ71D21.2, UPF0624 protein C6orf186.

Gen-ID: 728464