C1orf43 Antikörper (AA 11-100) (Alexa Fluor 594)

Produktnummer ABIN2810687

Produktdetails anti-C1orf43 Antikörper

Target: C1orf43 (Chromosome 1 Open Reading Frame 43 (C1orf43))

Bindungsspezifität: AA 11-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1orf43 Antikörper ist konjugiert mit Alexa Fluor 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf43

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Haltbarkeit: 12 months

Details zu C1orf43

Target: C1orf43 (Chromosome 1 Open Reading Frame 43 (C1orf43))

Andere Bezeichnung: C1orf43 (C1orf43 Produkte)

Synonyme: NICE-3 antikoerper, NS5ATP4 antikoerper, S863-3 antikoerper, c1orf43 antikoerper, chromosome 1 open reading frame 43 antikoerper, chromosome 1 open reading frame 43 L homeolog antikoerper, C1orf43 antikoerper, c1orf43.L antikoerper

Hintergrund:

C1orf43, also known as Hepatitis C virus NS5A-transactivated protein 4 and Protein NICE-3, is a 253 amino acid single-pass membrane protein. There are five isoforms of C1orf43 that are produced as a result of alternative splicing events. The gene encoding C1orf43 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Subcellular location: Nucleus

Synonyms: 4933434E20Rik, AI462154, C1orf43, CA043_HUMAN, Chromosome 1 open reading frame 43, HCV NS5A transactivated protein 4, HCV NS5A-transactivated protein 4, Hepatitis C virus NS5A transactivated protein 4, Hepatitis C virus NS5A-transactivated protein 4, HSPC012, Hypothetical protein LOC25912, MGC111001, NICE 3, NICE3, NS5ATP4, OTTHUMP00000034199, OTTHUMP00000034201, OTTHUMP00000034202, Protein NICE 3, Protein NICE-3, Riken cDNA 4933434E20, S863 3, S863-3, Uncharacterized protein C1orf43.

Gen-ID: 25912