MEAF6 Antikörper (AbBy Fluor® 594)

Produktnummer ABIN2810652

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MEAF6 in WB und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für MEAF6 Antikörper (AbBy Fluor® 594) (ABIN2810652)

Target: MEAF6 (MYST/Esa1-Associated Factor 6 (MEAF6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEAF6 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MEAF6 Antikörper (AbBy Fluor® 594)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf149

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MEAF6

Target: MEAF6 (MYST/Esa1-Associated Factor 6 (MEAF6))

Andere Bezeichnung: C1orf149

Hintergrund:

Synonyms: CDABP0189, Chromosome 1 open reading frame 149, Eaf6, FLJ11730, Hypothetical protein LOC64769, NY SAR 91, RP3 423B22.2, Sarcoma antigen NY SAR 91, EAF6_HUMAN.

Background: MEAF6, also known as Eaf6 or NY-SAR-91, is a 191 amino acid nuclear protein belonging to the EAF6 family. MEAF6 is a component of the NuA4 histone acetyltransferase complex, which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. The gene encoding MEAF6 localizes to chromosome 1 and, due to alternative splicing events, MEAF6 exists in at least three isoforms. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1 such as Hutchinson-Gilford progeria, Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.

Gen-ID: 64769