STAMBP Antikörper (AA 331-420) (AbBy Fluor® 594)
Kurzübersicht für STAMBP Antikörper (AA 331-420) (AbBy Fluor® 594) (ABIN2809704)
Target
Alle STAMBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 331-420
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Kreuzreaktivität
- Maus, Ratte
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Homologie
- Human,Dog,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human AMSH
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- STAMBP (STAM Binding Protein (STAMBP))
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Andere Bezeichnung
- AMSH
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Hintergrund
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Synonyms: Associated molecule with the SH3 domain of STAM, Endosome associated ubiquitin isopeptidase, Endosome-associated ubiquitin isopeptidase, STABP_HUMAN, STAM binding protein, STAM-binding protein, STAMBP.
Background: Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Functions at the endosome and is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7.
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Gen-ID
- 10617
Target
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