Vasopressin Antikörper (AbBy Fluor® 594)

Produktnummer ABIN2809496

Dieses Anti-Vasopressin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Vasopressin in IF (cc) und IF (p). Geeignet für Human und Maus.

Kurzübersicht für Vasopressin Antikörper (AbBy Fluor® 594) (ABIN2809496)

Target: Vasopressin (AVP) (Arginine Vasopressin (AVP))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vasopressin Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Vasopressin Antikörper (AbBy Fluor® 594)

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADH (CYFQNCPRG-NH? (Disulfide bond 1,6)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Vasopressin

Target: Vasopressin (AVP) (Arginine Vasopressin (AVP))

Andere Bezeichnung: ADH/ AVP/ ARVP

Hintergrund:

Synonyms: Antidiuretic Hormone, Arginine Vasopressin, ADH, Arginine vasopressin neurophysin II, ARVP, AVP, AVP NPII, AVRP, Vasopressin neurophysin 2 copeptin precursor, Vasopressin neurophysin II copeptin, VP.

Background: Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria.

Gen-ID: 551

UniProt: P01185

Pathways: cAMP Metabolic Process