MPZL2 Antikörper (AA 61-160) (AbBy Fluor® 594)

Produktnummer ABIN2808816

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MPZL2 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MPZL2 Antikörper (AA 61-160) (AbBy Fluor® 594) (ABIN2808816)

Target: MPZL2 (Myelin Protein Zero-Like 2 (MPZL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPZL2 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MPZL2 Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 61-160

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MPZL2/EVA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MPZL2

Target: MPZL2 (Myelin Protein Zero-Like 2 (MPZL2))

Andere Bezeichnung: MPZL2/EVA1

Hintergrund:

Synonyms: Epithelial V like antigen 1, epithelial V-like antigen, EVA, EVA1, MPZL2, MPZL2 myelin protein zero like 2, myelin protein zero-like 2, Myelin protein zero like protein 2, MPZL2_HUMAN.

Background: Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain, a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].