DYNC1LI1 Antikörper (AA 451-523) (FITC)

Produktnummer ABIN2808049

Produktdetails anti-DYNC1LI1 Antikörper (FITC)

Target: DYNC1LI1 (Dynein, Cytoplasmic 1, Light Intermediate Chain 1 (DYNC1LI1))

Bindungsspezifität: AA 451-523

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYNC1LI1 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNCLI1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DYNC1LI1

Target: DYNC1LI1 (Dynein, Cytoplasmic 1, Light Intermediate Chain 1 (DYNC1LI1))

Andere Bezeichnung: DNCLI1 (DYNC1LI1 Produkte)

Hintergrund:

Synonyms: LIC1, DNCLI1, Cytoplasmic dynein 1 light intermediate chain 1, Dynein light chain A, DLC-A, Dynein light intermediate chain 1, cytosolic, DYNC1LI1

Background: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

Gen-ID: 51143

UniProt: Q9Y6G9