ZWINT Antikörper (AA 85-170) (AbBy Fluor® 594)
Kurzübersicht für ZWINT Antikörper (AA 85-170) (AbBy Fluor® 594) (ABIN2807720)
Target
Alle ZWINT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 85-170
-
Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human ZWINT
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- ZWINT (ZW10 Interactor (ZWINT))
-
Andere Bezeichnung
- ZWINT
-
Hintergrund
-
Synonyms: HZwint1, KNTC 2 AP, KNTC2AP, MGC 117174, MGC117174, ZW10 interacting protein 1, ZW10 interactor, ZWINT 1, ZWINT1, ZWINT-1, ZWINT_HUMAN.
Background: ZWINT is a component of the MIS12 complex, which is required for kinetochore function and spindle checkpoint activity. ZWINT interacts with ZW10 and targets it to the kinetochore at prometaphase. ZWINT is detectable on the kinetochore till late anaphase. Inhibition of ZWINT expression results in chromosome missegregation, spindle checkpoint failure and, ultimately, cell death upon cytokinesis.
-
Gen-ID
- 11130
Target
-