ZBTB46 Antikörper (AbBy Fluor® 594)
Kurzübersicht für ZBTB46 Antikörper (AbBy Fluor® 594) (ABIN2807621)
Target
Alle ZBTB46 (ZNF340) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Maus
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Homologie
- Human,Rat,Sheep,Horse,Chicken
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human ZBTB46/BTBD4
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Isotyp
- IgG
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Applikationshinweise
- IF(IHC-P) 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))
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Andere Bezeichnung
- ZBTB46/ BTBD4
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Hintergrund
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Synonyms: BTB/POZ domain containing protein 4, BTBD4, RINZF, Zinc finger and BTB domain containing 46, Zinc finger and BTB domain containing protein 46, Zinc finger protein 340, ZNF340, ZBT46_HUMAN.
Background: BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
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Gen-ID
- 140685
Target
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