UBE2W Antikörper (AA 71-151) (AbBy Fluor® 594)

Produktnummer ABIN2807357

Dieses Anti-UBE2W-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UBE2W in IF (cc) und IF (p). Geeignet für Maus und Ratte.

Kurzübersicht für UBE2W Antikörper (AA 71-151) (AbBy Fluor® 594) (ABIN2807357)

Target: UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2W Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-UBE2W Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 71-151

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UBE2W

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu UBE2W

Target: UBE2W (Ubiquitin-Conjugating Enzyme E2W (UBE2W))

Andere Bezeichnung: UBE2W

Hintergrund:

Synonyms: hUBC 16, hUBC16, Probable ubiquitin conjugating enzyme E2 W, Probable ubiquitin-conjugating enzyme E2 W, UBE 2W, ube2w, UBE2W_HUMAN, Ubiquitin carrier protein W, Ubiquitin conjugating enzyme 16, Ubiquitin conjugating enzyme E2 W, Ubiquitin conjugating enzyme E2W, Ubiquitin protein ligase W, Ubiquitin-protein ligase W, FLJ11011.

Background: Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins. Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). As an E2 class enzyme, UBE2W (Ubiquitin-conjugating enzyme E2 W), also known as Ubiquitin carrier protein W, is a 151 amino acid that catalyzes the conjugation of ubiquitin to proteins that are meant for lysosomal degradation. Functioning as a homodimer, UBE2W is widely expressed, with highest levels in testis. There are two isoforms of UBE2W that are produced as a result of alternative splicing events.

Gen-ID: 55284