TESK2 Antikörper (AA 301-400) (AbBy Fluor® 594)
Kurzübersicht für TESK2 Antikörper (AA 301-400) (AbBy Fluor® 594) (ABIN2806963)
Target
Alle TESK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 301-400
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Homologie
- Human,Mouse,Rat,Horse,Chicken,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human TESK2
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- TESK2 (Testis-Specific Kinase 2 (TESK2))
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Andere Bezeichnung
- TESK2
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Hintergrund
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Synonyms: Dual specicity testis specic protein kinase 2, Dual specicity testis-specic protein kinase 2, MGC29168, OTTHUMP00000009093, RP23-109A3.2, Tesk2, TESK2_HUMAN, Testicular protein kinase 2, Testis specic kinase 2.
Background: TESK2 is a nuclear protein that belongs to the protein kinase superfamily and is expressed in testis and prostate. Functioning as a dual-specificity protein kinase, TESK2 catalyzes the ATP-dependent phosphorylation of substrates and autophosphorylation on tyrosine and serine/threonine residues, thereby mediating intracellular signal transduction pathways. TESK2 requires magnesium as a cofactor and its catalytic activity is thought to play an important role in meiotic events such as spermatogenesis. TESK2 contains one protein kinase domain that is 65 % identical to the kinase domain found in TESK1 (testicular protein kinase 1), suggesting a similar role for these proteins in phosphorylation events. Three isoforms of TESK2 are expressed due to alternative splicing.
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Gen-ID
- 10420
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Pathways
- Cell-Cell Junction Organization
Target
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