SRPK1 Antikörper (AA 551-655) (AbBy Fluor® 594)

Produktnummer ABIN2806667

Dieses Anti-SRPK1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SRPK1 in IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für SRPK1 Antikörper (AA 551-655) (AbBy Fluor® 594) (ABIN2806667)

Target: SRPK1 (SRSF Protein Kinase 1 (SRPK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRPK1 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SRPK1 Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 551-655

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SRPK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SRPK1

Target: SRPK1 (SRSF Protein Kinase 1 (SRPK1))

Andere Bezeichnung: SRPK1

Hintergrund:

Synonyms: Serine/arginine rich protein specic kinase 1, Serine/arginine-rich protein-specic kinase 1, Serine/threonine protein kinase SRPK1, Serine/threonine-protein kinase SRPK1, SFRS protein kinase 1, SR protein kinase 1, SR protein specic kinase 1, SR-protein-specic kinase 1, SRPK1, SRPK1_HUMAN.

Background: Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Hyperphosphorylates RS domain-containing proteins such as SFRS1, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase. Locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.

Gen-ID: 6732

Pathways: Toll-Like Receptors Cascades