SMYD2A Antikörper (AbBy Fluor® 594)
Kurzübersicht für SMYD2A Antikörper (AbBy Fluor® 594) (ABIN2806519)
Target
Alle SMYD2A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human SMYD2
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Isotyp
- IgG
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Applikationshinweise
- IF(IHC-P)(1:50-200)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at 4°C
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Haltbarkeit
- 12 months
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- SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
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Andere Bezeichnung
- SMYD2
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Hintergrund
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Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.
Synonyms: HSKM B, HSKM-B, HSKMB, Histone methyltransferase SMYD2, HSKM-B, Lysine N-methyltransferase 3C, MGC119305, N lysine methyltransferase SMYD2, N-lysine methyltransferase SMYD2, SET and MYND domain containing 2, SET and MYND domain containing protein 2, SET and MYND domain-containing protein 2, Smyd2, SMYD2_HUMAN, Zinc finger MYND domain containing 14, ZMYND14. -
Gen-ID
- 56950
Target
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