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Prostacyclin Receptor Antikörper (AA 101-200) (AbBy Fluor® 594)

This anti-Prostacyclin Receptor antibody (ABIN2805608) is a Rabbit Polyclonal antibody detecting Prostacyclin Receptor in IF (cc), IF (p). Suitable for Human.
Produktnummer ABIN2805608

Quick Overview for Prostacyclin Receptor Antikörper (AA 101-200) (AbBy Fluor® 594) (ABIN2805608)

Target

Alle Prostacyclin Receptor (PTGIR) Antikörper anzeigen
Prostacyclin Receptor (PTGIR)

Reaktivität

  • 43
  • 11
  • 5
  • 2
  • 2
Human

Wirt

  • 44
  • 4
Kaninchen

Klonalität

  • 44
  • 4
Polyklonal

Konjugat

  • 22
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Prostacyclin Receptor Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation

  • 24
  • 16
  • 15
  • 12
  • 12
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200

    Kreuzreaktivität

    Human

    Homologie

    Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Prostaglandin I2 Receptor

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Prostacyclin Receptor (PTGIR)

    Andere Bezeichnung

    Prostaglandin I2 Receptor

    Hintergrund

    Synonyms: IP, PGI receptor, PGI2 receptor, PI2R_HUMAN, PRIPR, Prostacyclin receptor, Prostaglandin I2 receptor, Prostanoid IP receptor, PTGIR.

    Background: Cyclooxygenases metabolize arachidonate to five primary prostanoids: PGE2, PGF2?, PGI2, TXA2 and PGD2. These lipid mediators interact with specific members of G protein-coupled prostanoid receptors, designated EP, FP, IP, TP and DP, respectively. The IP Receptor binds prostacyclin, PGI2, the main pro-stanoid synthesized by vascular tissues.Upon binding to the IP Receptor, prostacyclin activates adenylate cyclase primarily through the Gas protein. The gene encoding the human IP Receptor is located on chromosome 19. It is expressed as a glycosylated and phosphorylated protein, which is abundantly expressed in vascular tissues such as aorta, lung, atrium and ventricle, as well as in kidney, thymus, spleen and neurons.

    Pathways

    cAMP Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling
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