TMEM123 Antikörper (AA 101-180) (AbBy Fluor® 594)

Produktnummer ABIN2805485

Dieses Anti-TMEM123-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TMEM123 in WB, FACS, IF (cc) und IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für TMEM123 Antikörper (AA 101-180) (AbBy Fluor® 594) (ABIN2805485)

Target: TMEM123 (Transmembrane Protein 123 (TMEM123))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM123 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TMEM123 Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 101-180

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Porimin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TMEM123

Target: TMEM123 (Transmembrane Protein 123 (TMEM123))

Andere Bezeichnung: Porimin

Hintergrund:

Synonyms: KCT3, Keratinocytes associated transmembrane protein 3, Pro oncosis receptor inducing membrane injury, Serine/threonine rich receptor, TMEM123, Transmembrane protein 123, PORIM_HUMAN.

Background: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

Gen-ID: 114908

Pathways: Regulation of Cell Size