PIWIL1 Antikörper (AA 551-650) (AbBy Fluor® 594)

Produktnummer ABIN2805361

Der Kaninchen Polyklonal Anti-PIWIL1-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, PIWIL1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für PIWIL1 Antikörper (AA 551-650) (AbBy Fluor® 594) (ABIN2805361)

Target: PIWIL1 (Piwi-Like 1 (PIWIL1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIWIL1 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PIWIL1 Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 551-650

Kreuzreaktivität: Human, Maus

Homologie: Rat,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from chicken PIWIL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PIWIL1

Target: PIWIL1 (Piwi-Like 1 (PIWIL1))

Andere Bezeichnung: PIWIL1

Hintergrund:

Synonyms: PIWI, Piwi-like protein 1, PIWIL1

Background: Plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 3 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity).

Gen-ID: 416804

UniProt: A6N7Y9