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MEGF10 Antikörper (Multiple EGF-Like-Domains 10) (Alexa Fluor 594) Primary Antibody

MEGF10 Reaktivität: Human, Maus, Ratte IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 594
Produktnummer ABIN2804104
$442.20
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 16 Werktagen
  • Target
    MEGF10
    Reaktivität
    Human, Maus, Ratte
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Konjugat
    Dieser MEGF10 Antikörper ist konjugiert mit Alexa Fluor 594
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MEGF10
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 4°C
    Haltbarkeit
    12 months
  • Target
    MEGF10
    Andere Bezeichnung
    MEGF10 (MEGF10 Antibody Abstract)
    Synonyme
    EMARDD, 3000002B06Rik, Gm331, multiple EGF-like domains 10, multiple EGF like domains 10, multiple EGF-like-domains 10, Megf10, MEGF10
    Hintergrund

    MEGF10 is a 1,140 amino acid protein encoded by the human gene MEGF10. MEGF10 belongs to the MEGF family and contains fifteen EGF-like domains and one EMI domain. The engulfment of dying cells is a specialized form of phagocytosis that is highly conserved across evolution and is mediated by the concerted action of several molecules. MEGF10 is an engulfment receptor protein that localizes to the plasma membrane in a punctuated pattern. The MEGF10 protein shares structural similarities with nematode engulfment receptor cell death abnormal-1 (CED-1). MEGF10 function is modulated by the ATP binding cassette transporter ABCA1, which is an ortholog to CED-7. It is expressed at the cell surface in clusters around cell corpses during engulfment, and during the engulfment of apoptotic thymocytes is recruited to the bottom of the forming phagocytic cup.

    Subcellular location: Extracellular

    Synonyms: MEG10_HUMAN, MEGF protein, megf10, Multiple EGF-like domains protein 10, multiple EGF-like-domains 10, Multiple epidermal growth factor-like domains 10, Multiple epidermal growth factor-like domains protein 10.

    Gen-ID
    84466
    Pathways
    Regulation of Muscle Cell Differentiation
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