DUSP5 Antikörper (AA 221-320) (AbBy Fluor® 594)
Kurzübersicht für DUSP5 Antikörper (AA 221-320) (AbBy Fluor® 594) (ABIN2803336)
Target
Alle DUSP5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 221-320
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human DUSP5
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))
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Andere Bezeichnung
- DUSP5
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Hintergrund
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Synonyms: Dual specicity protein phosphatase 5, Dual specicity protein phosphatase hVH 3, Dual specicity protein phosphatase hVH3, DUSP 5, DUSP, HVH 3, HVH3, Serine/threonine specic protein phosphatase, VH 3, VH1 like phosphatase 3, VH3, DUS5_HUMAN.
Background: Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), MKP-2, MKP-3, MKP-4, MKP-5, MKP-6, MKP-7, MKP-X, VHR, VHY, PAC1, hVH-3 (B23), hVH-5, PYST2, DUSP1, DUSP5, DUSP8, PIR1 and SKRP1. DUSP5 is a nuclear phosphoprotein that displays phosphatase activity toward several different substrates. It shows the highest relative activity toward ERK1.
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Gen-ID
- 1847
Target
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