SMYD2A Antikörper (AA 351-433)

Produktnummer ABIN2803151

Produktdetails anti-SMYD2A Antikörper

Target: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Bindungsspezifität: AA 351-433

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMYD2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SMYD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SMYD2A

Target: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Andere Bezeichnung: SMYD2 (SMYD2A Produkte)

Synonyme: HSKM-B antikoerper, KMT3C antikoerper, ZMYND14 antikoerper, 1110020E07Rik antikoerper, 4930402C15 antikoerper, Zmynd14 antikoerper, smyd2-a antikoerper, im:7146196 antikoerper, smyd2 antikoerper, wu:fc02f02 antikoerper, zgc:110553 antikoerper, si:dkey-121j17.3 antikoerper, zgc:136609 antikoerper, SET and MYND domain containing 2 antikoerper, SET and MYND domain containing 2 S homeolog antikoerper, SET and MYND domain containing 2a antikoerper, SET and MYND domain containing 2b antikoerper, SMYD2 antikoerper, Smyd2 antikoerper, smyd2.S antikoerper, smyd2a antikoerper, smyd2b antikoerper

Hintergrund:

Synonyms: KMT3C, HSKM-B, ZMYND14, N-lysine methyltransferase SMYD2, Histone methyltransferase SMYD2, Lysine N-methyltransferase 3C, SET and MYND domain-containing protein 2, SMYD2

Background: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.

Gen-ID: 56950

UniProt: Q9NRG4