FOLR2 Antikörper

Produktnummer ABIN2800693

Dieses Maus Monoklonal-Antikörper erkennt spezifisch FOLR2 in WB, FACS, IP und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FOLR2 Antikörper (ABIN2800693)

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOLR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: EM-35

Produktdetails anti-FOLR2 Antikörper

Verwendungszweck: Anti-FOLR2 Purified

Spezifität: The mouse monoclonal antibody EM-35 recognizes an extracellular epitope on FOLR2, a 30-40 kDa cell surface protein serving as a receptor for folic acid.

Keine Kreuzreaktivität: Maus

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: BW5147alpha,beta- cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blotting: Non-reducing conditions.
Flow cytometry: Recommended dilution: 1-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Andere Bezeichnung: FOLR2

Hintergrund: Folate receptor beta,FOLR2 (folate receptor beta) is a cell surface protein that was originally thought to be specific for placenta, but it can be also expressed in other tissues, including hematopoietic cells. Its expression is increased in malignant tissues. FOLR2 may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. FOLR2 is a marker for macrophages generated in the presence of M-CSF (M2), including M2-like tumor-associated macrophages, which exert potent immunosuppressive functions within the tumor environment, but not GM-CSF (M1), and whose expression correlates with increased folate uptake ability.,Folate receptor beta, FBP, FR-P3, FR-BETA, BETA-HFR, FBP/PL-1

Gen-ID: 2350

UniProt: P14207

Pathways: Dicarboxylic Acid Transport