Asialoglycoprotein Receptor 1 Antikörper (N-Term)

Produktnummer ABIN2798934

Dieses Anti-Asialoglycoprotein Receptor 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Asialoglycoprotein Receptor 1 in WB. Geeignet für Human.

Kurzübersicht für Asialoglycoprotein Receptor 1 Antikörper (N-Term) (ABIN2798934)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Asialoglycoprotein Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Asialoglycoprotein Receptor 1 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Verwendungszweck: Rabbit Anti-Human ASGR1 (N-term) Antibody

Immunogen: This ASGR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ASGR1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000ASGR1 Antibody (N-term) .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Andere Bezeichnung: ASGR1

Hintergrund:

Target Description: Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

Gene Symbol: ASGR1

Molekulargewicht: 33186 Da

Gen-ID: 432

UniProt: P07306

Pathways: Thyroid Hormone Synthesis