TNNI2 Antikörper (N-Term)

Produktnummer ABIN2798893

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TNNI2 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TNNI2 Antikörper (N-Term) (ABIN2798893)

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNNI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TNNI2 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Verwendungszweck: Rabbit Anti-Human TNNI2 (N-term) Antibody

Immunogen: This TNNI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TNNI2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of lysate from human skeletal muscle tissue lysate, using TNNI2 Antibody (N-term) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 μg per lane.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu TNNI2

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Andere Bezeichnung: TNNI2

Hintergrund:

Target Description: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].

Gene Symbol: TNNI2

Molekulargewicht: 21339 Da

Gen-ID: 7136

UniProt: P48788