POLG Antikörper (C-Term)
Kurzübersicht für POLG Antikörper (C-Term) (ABIN2798829)
Target
Alle POLG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1120-1148, C-Term
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Verwendungszweck
- Rabbit Anti-Mouse POLG (C-term) Antibody
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Immunogen
- This POLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1120-1148 amino acids from the C-terminal region of human POLG.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50, IF: 1:10-50, IHC: 1:10-50POLG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.460 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- POLG (Polymerase (DNA Directed), gamma (POLG))
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Andere Bezeichnung
- POLG
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Hintergrund
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Target Description: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.
Gene Symbol: POLG
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Molekulargewicht
- 139562 Da
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Gen-ID
- 5428
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UniProt
- P54098
Target
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