Septin 5 Antikörper (N-Term)

Produktnummer ABIN2798741

Der Kaninchen Polyklonal Anti-Septin 5-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Septin 5 in Proben von Human zu detektieren.

Kurzübersicht für Septin 5 Antikörper (N-Term) (ABIN2798741)

Target: Septin 5 (SEPT5)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Septin 5 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Verwendungszweck: Rabbit Anti-Human SEPT5 (N-term) Antibody

Immunogen: This SEPT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEPT5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of lysate from human brain tissue lysate, using SEPT5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu Septin 5

Target: Septin 5 (SEPT5)

Andere Bezeichnung: SEPT5

Hintergrund:

Target Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq].

Gene Symbol: SEPT5

Molekulargewicht: 42777 Da

Gen-ID: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis