TADA3L Antikörper (C-Term)
Kurzübersicht für TADA3L Antikörper (C-Term) (ABIN2798740)
Target
Alle TADA3L (TADA3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 386-414, C-Term
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Verwendungszweck
- Rabbit Anti-Human TADA3L (C-term) Antibody
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Immunogen
- This TADA3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-414 amino acids from the C-terminal region of human TADA3L.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IF: 1:10-50TADA3L Antibody (C-term) . TADA3L immunoreactivity is localized to Nucleus significantly. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
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Andere Bezeichnung
- TADA3L
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Hintergrund
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Target Description: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq].
Gene Symbol: TADA3
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Molekulargewicht
- 48902 Da
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Gen-ID
- 10474
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UniProt
- O75528
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
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