PRDM6 Antikörper (N-Term)
Kurzübersicht für PRDM6 Antikörper (N-Term) (ABIN2798584)
Target
Alle PRDM6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 44-72, N-Term
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Verwendungszweck
- Rabbit Anti-Human PRDM6 (N-term) Antibody
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Immunogen
- This PRDM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human PRDM6.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot
Recommended Dilutions
WB: 1:1000PRDM6 Antibody (N-term) . -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.350 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- PRDM6 (PR Domain Containing 6 (PRDM6))
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Andere Bezeichnung
- PRDM6
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Hintergrund
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Target Description: Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression (By similarity).
Gene Symbol: PRDM6
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Molekulargewicht
- 64452 Da
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Gen-ID
- 93166
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UniProt
- Q9NQX0
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Pathways
- Regulation of Muscle Cell Differentiation
Target
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