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PRDM6 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PRDM6 in WB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN2798584

Kurzübersicht für PRDM6 Antikörper (N-Term) (ABIN2798584)

Target

Alle PRDM6 Antikörper anzeigen
PRDM6 (PR Domain Containing 6 (PRDM6))

Reaktivität

  • 17
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 17
Kaninchen

Klonalität

  • 17
Polyklonal

Konjugat

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PRDM6 Antikörper ist unkonjugiert

Applikation

  • 17
  • 8
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 44-72, N-Term

    Verwendungszweck

    Rabbit Anti-Human PRDM6 (N-term) Antibody

    Immunogen

    This PRDM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human PRDM6.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Western Blot
    Recommended Dilutions
    WB: 1:1000PRDM6 Antibody (N-term) .

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.350 mg/mL

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    2-8°C (short-term), -20°C (long-term)
  • Target

    PRDM6 (PR Domain Containing 6 (PRDM6))

    Andere Bezeichnung

    PRDM6

    Hintergrund

    Target Description: Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression (By similarity).

    Gene Symbol: PRDM6

    Molekulargewicht

    64452 Da

    Gen-ID

    93166

    UniProt

    Q9NQX0

    Pathways

    Regulation of Muscle Cell Differentiation
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