PUF60 Antikörper (N-Term)
Kurzübersicht für PUF60 Antikörper (N-Term) (ABIN2798565)
Target
Alle PUF60 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 15-43, N-Term
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Verwendungszweck
- Rabbit Anti-Human PUF60 (N-term) Antibody
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Immunogen
- This PUF60 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the N-terminal region of human PUF60.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot
Recommended Dilutions
WB: 1:1000PUF60 Antibody (N-term) . -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.350 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
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Andere Bezeichnung
- PUF60
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Hintergrund
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Target Description: The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
Gene Symbol: PUF60
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Molekulargewicht
- 59875 Da
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Gen-ID
- 22827
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UniProt
- Q9UHX1
Target
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