RNF19A Antikörper (Center)

Produktnummer ABIN2798497

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RNF19A in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RNF19A Antikörper (Center) (ABIN2798497)

Target: RNF19A (Ring Finger Protein 19A (RNF19A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF19A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RNF19A Antikörper

Bindungsspezifität: AA 384-413, Center

Verwendungszweck: Rabbit Anti-Human RNF19A (Center) Antibody

Immunogen: This RNF19A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-413 amino acids from the Central region of human RNF19A.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50RNF19A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu RNF19A

Target: RNF19A (Ring Finger Protein 19A (RNF19A))

Andere Bezeichnung: RNF19A

Hintergrund:

Target Description: The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.

Gene Symbol: RNF19A

Molekulargewicht: 90696 Da

Gen-ID: 25897

UniProt: Q9NV58