CDH6 Antikörper (C-Term)

Produktnummer ABIN2798460

Dieses Anti-CDH6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CDH6 in WB, IHC und FACS. Geeignet für Human.

Kurzübersicht für CDH6 Antikörper (C-Term) (ABIN2798460)

Target: CDH6 (K-Cadherin (CDH6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDH6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-CDH6 Antikörper

Bindungsspezifität: AA 665-695, C-Term

Verwendungszweck: Rabbit Anti-Human K Cadherin (CDH6) (C-term) Antibody

Immunogen: This K Cadherin (CDH6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-695 amino acids from the C-terminal region of human K Cadherin (CDH6).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of anti-DH6 Antibody (C-term) (RB14082) in 293 cell line lysates (35 μg/lane). DH6(arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CDH6 antibody (C-term) . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu CDH6

Target: CDH6 (K-Cadherin (CDH6))

Andere Bezeichnung: K Cadherin

Hintergrund:

Target Description: CDH6 is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of the CDH6 gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.

Gene Symbol: CDH6

Molekulargewicht: 88309 Da

Gen-ID: 1004

UniProt: P55285

Pathways: Cell-Cell Junction Organization