Cofilin 2 Antikörper (N-Term)
Kurzübersicht für Cofilin 2 Antikörper (N-Term) (ABIN2798438)
Target
Alle Cofilin 2 (CFL2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 25-54, N-Term
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Verwendungszweck
- Rabbit Anti-Human CFL2 (N-term) Antibody
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Immunogen
- This CFL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human CFL2.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of lysate from NCI-H1299 cell line, using CFL2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.480 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- Cofilin 2 (CFL2)
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Andere Bezeichnung
- CFL2
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Hintergrund
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Target Description: This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Gene Symbol: CFL2
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Molekulargewicht
- 18737 Da
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Gen-ID
- 1073
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UniProt
- Q9Y281
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Pathways
- Caspase Kaskade in der Apoptose
Target
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