Surfactant Protein C Antikörper (N-Term)

Produktnummer ABIN2797711

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Surfactant Protein C in WB und IF. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Surfactant Protein C Antikörper (N-Term) (ABIN2797711)

Target: Surfactant Protein C (SFTPC)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Surfactant Protein C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-Surfactant Protein C Antikörper

Bindungsspezifität: AA 1-30, N-Term

Verwendungszweck: Rabbit Anti-Mouse SFTPC (N-term) Antibody

Immunogen: This SFTPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SFTPC.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Immunofluorescence, Western Blot
Recommended Dilutions
IF: 1:25, WB: 1:1000Immunofluorescent analysis of Human lung tissues, using SFTPC Antibody (N-term) .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.340 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu Surfactant Protein C

Target: Surfactant Protein C (SFTPC)

Andere Bezeichnung: SFTPC

Hintergrund:

Target Description: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Gene Symbol: SFTPC

Molekulargewicht: 21053 Da

Gen-ID: 6440

UniProt: P11686