WT1 Antikörper (AA 346-375)

Produktnummer ABIN2797552

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch WT1 in IHC, IF, FACS und WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für WT1 Antikörper (AA 346-375) (ABIN2797552)

Target: WT1 (Wilms Tumor 1 (WT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB)

Produktdetails anti-WT1 Antikörper

Bindungsspezifität: AA 346-375

Verwendungszweck: Rabbit Anti-Human WT1 (Center E361) Antibody

Immunogen: This WT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the Central region of human WT1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, IF: 1:10-50, FC: 1:10-50WT1 Antibody (Center E361) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.300 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Andere Bezeichnung: WT1

Hintergrund:

Target Description: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq].

Gene Symbol: WT1

Molekulargewicht: 49188 Da

Gen-ID: 7490

UniProt: P19544

Pathways: Tube Formation