USP16 Antikörper (Center)

Produktnummer ABIN2796351

Dieses Anti-USP16-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von USP16 in WB. Geeignet für Human.

Kurzübersicht für USP16 Antikörper (Center) (ABIN2796351)

Target: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-USP16 Antikörper

Bindungsspezifität: AA 386-416, Center

Verwendungszweck: Rabbit Anti-Human USP16 (Center) Antibody

Immunogen: This USP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-416 amino acids from the Central region of human USP16.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of anti-USP16 Pab was detected using the purified Pab.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.0 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu USP16

Target: USP16 (Ubiquitin Specific Peptidase 16 (USP16))

Andere Bezeichnung: USP16

Hintergrund:

Target Description: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Gene Symbol: USP16

Molekulargewicht: 93570 Da

Gen-ID: 10600

UniProt: Q9Y5T5