SGOL2 Antikörper (Center)
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- Target Alle SGOL2 Antikörper anzeigen
- SGOL2 (Shugoshin-Like 2 (SGOL2))
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Bindungsspezifität
- AA 391-419, Center
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SGOL2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit Anti-Human SGOL2 (Center) Antibody
- Immunogen
- This SGOL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human SGOL2.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SGOL2 Primärantikörper
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- Applikationshinweise
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Western Blot
Recommended Dilutions
WB: 1:1000SGOL2 Antibody (Center) . - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- Target
- SGOL2 (Shugoshin-Like 2 (SGOL2))
- Andere Bezeichnung
- SGOL2 (SGOL2 Produkte)
- Synonyme
- SGO2 antikoerper, TRIPIN antikoerper, 1110007N04Rik antikoerper, 4932411A20Rik antikoerper, 5730576N04Rik antikoerper, AU018846 antikoerper, AV008062 antikoerper, D1Ertd8e antikoerper, Tripin antikoerper, shugoshin 2 antikoerper, shugoshin 2A antikoerper, SGO2 antikoerper, Sgo2a antikoerper
- Hintergrund
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Target Description: Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.
Gene Symbol: SGOL2
- Molekulargewicht
- 144739 Da
- Gen-ID
- 151246
- UniProt
- Q562F6
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