VEGF1 Antikörper (N-Term)

Produktnummer ABIN2794871

Produktdetails anti-VEGF1 Antikörper

Target: VEGF1 (PVF1) (PDGF and VEGF-Related Factor 1 (PVF1))

Bindungsspezifität: AA 66-95, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VEGF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit Anti-Human VEGF1 (N-term) Antibody

Immunogen: This VEGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human VEGF1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of VEGF1 Antibody (N-term) polyclonal antibody. Molecular weight of monomeric VEGF1 is 27042 Da, higher observed molecular weight band is consistent with common form of disulfide linked homodimer.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.0 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu VEGF1

Target: VEGF1 (PVF1) (PDGF and VEGF-Related Factor 1 (PVF1))

Andere Bezeichnung: VEGF1 (PVF1 Produkte)

Hintergrund:

Target Description: VEGF1 is a member of the PDGF/VEGF growth factor family and and is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF1 have been associated with proliferative and nonproliferative diabetic retinopathy.

Gene Symbol: VEGFA

Molekulargewicht: 27042 Da

Gen-ID: 7422

UniProt: P15692