Importin 11 Antikörper (C-Term)

Produktnummer ABIN2793758

Der Kaninchen Polyklonal Anti-Importin 11-Antikörper wurde für WB und IP validiert. Er ist geeignet, Importin 11 in Proben von Human zu detektieren.

Kurzübersicht für Importin 11 Antikörper (C-Term) (ABIN2793758)

Target: Importin 11 (IPO11)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Importin 11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-Importin 11 Antikörper

Bindungsspezifität: AA 891-920, C-Term

Verwendungszweck: Rabbit Anti-Human IPO11 (C-term) Antibody

Immunogen: This IPO11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 891-920 amino acids from the C-terminal region of human IPO11.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of IPO11 Antibody (C-term) was detected using the purified Pab.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu Importin 11

Target: Importin 11 (IPO11)

Andere Bezeichnung: IPO11

Hintergrund:

Target Description: IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).

Gene Symbol: IPO11

Molekulargewicht: 112535 Da

Gen-ID: 51194

UniProt: Q9UI26

Pathways: Protein targeting to Nucleus