CFLA Antikörper (Center)
Kurzübersicht für CFLA Antikörper (Center) (ABIN2793618)
Target
Reaktivität
Wirt
Klonalität
Applikation
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Bindungsspezifität
- AA 145-174, Center
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Verwendungszweck
- Rabbit Anti-Human CFLAR (Center) Antibody
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Immunogen
- This CFLAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human CFLAR.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, FC: 1:10-50Western blot analysis of CFLAR Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 2.000 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- CFLA (VVL) (POU Domain Protein CF1A (VVL))
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Andere Bezeichnung
- CFLA
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Hintergrund
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Target Description: Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.
Gene Symbol: CFLAR
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Molekulargewicht
- 55344 Da
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Gen-ID
- 8837
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UniProt
- O15519
Target
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