Transglutaminase Antikörper (AA 429-458)

Produktnummer ABIN2793240

Dieses Anti-Transglutaminase-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Transglutaminase in WB, IHC und IF. Geeignet für Human.

Kurzübersicht für Transglutaminase Antikörper (AA 429-458) (ABIN2793240)

Target: Transglutaminase

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transglutaminase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Transglutaminase Antikörper

Bindungsspezifität: AA 429-458

Verwendungszweck: Rabbit Anti-Human Transglutaminase (TGM2) (Center K444) Antibody

Immunogen: This Transglutaminase (TGM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 429-458 amino acids from the Central region of human Transglutaminase (TGM2).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunofluorescence, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IF: 1:10-50, IHC: 1:10-50TGM2 Antibody (Center K444) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.0 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu Transglutaminase

Target: Transglutaminase

Hintergrund:

Target Description: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.

Gene Symbol: TGM2

Molekulargewicht: 77329 Da

Gen-ID: 7052

UniProt: P21980