MAX Antikörper (N-Term)

Produktnummer ABIN2792669

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAX in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund und Zebrafisch (Danio rerio).

Kurzübersicht für MAX Antikörper (N-Term) (ABIN2792669)

Target: MAX (MYC Associated Factor X (MAX))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAX Antikörper

Bindungsspezifität: N-Term

Sequenz: MSDNDDIEVE SDADKRAHHN ALERKRRDHI KDSFHSLRDS VPSLQGEKAS

Kreuzreaktivität: Hund, Huhn, Human, Maus, Ratte (Rattus)

Homologie: Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against MAX. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human MAX

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-MAX Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 151 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAX

Target: MAX (MYC Associated Factor X (MAX))

Andere Bezeichnung: MAX

Hintergrund: MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown. The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
Alias Symbols: MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, orf1, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8
Protein Interaction Partner: USP37, UNC45A, BANP, FBXW11, MXI1, RPL35, TUBA1A, RPL34, GABBR1, FUS, FTH1, MYC, MXD1, MGA, PLIN3, HSP90AA1, TCF3, MYCN, CPSF6, ARL6IP5, KMT2D, HNRNPH2, DYNC1H1, CSTF2, SNIP1, PPP1CC, PPP1CB, PPP1CA, USF1, PCGF6, EP400, DMAP1, WDR5, BRD8, KAT5, MNT, MAX,
Protein Size: 151

Molekulargewicht: 17 kDa

Gen-ID: 4149

NCBI Accession: NM_145112, NP_660087

UniProt: P61244

Pathways: Mitotic G1-G1/S Phases