NHLH1 Antikörper (N-Term)

Produktnummer ABIN2792658

Produktdetails anti-NHLH1 Antikörper

Target: NHLH1 (Nescient Helix Loop Helix 1 (NHLH1))

Bindungsspezifität: N-Term

Reaktivität: Human, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NHLH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GGPGGGQARG PEPGEPGRKD LQHLSREERR RRRRATAKYR TAHATRERIR

Kreuzreaktivität: Rind (Kuh), Hund, Human

Homologie: Cow: 92%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NHLH1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NHLH1

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-NHLH1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human heart.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 133 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NHLH1

Target: NHLH1 (Nescient Helix Loop Helix 1 (NHLH1))

Andere Bezeichnung: HEN1 (NHLH1 Produkte)

Hintergrund: The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCLThe helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments.
Alias Symbols: HEN1, NSCL, NSCL1, bHLHa35
Protein Interaction Partner: CENPP, PIM1, INO80E, PSME2, HIVEP1, ELAVL1, LMO4, CSRP3, LMO1, LMO2, xlmo1, TCF3,
Protein Size: 133

Molekulargewicht: 14 kDa

Gen-ID: 4807

NCBI Accession: NM_005598, NP_005589

UniProt: Q02575