CEBPA Antikörper (N-Term)

Produktnummer ABIN2792649

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CEBPA in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Rind (Kuh), Meerschweinchen und Schwein.

Kurzübersicht für CEBPA Antikörper (N-Term) (ABIN2792649)

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEBPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CEBPA Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CEBPA Antibody - N-terminal region

Sequenz: GGICEHETSI DISAYIDPAA FNDEFLADLF QHSRQQEKAK AAVGPTGGGG

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte (Rattus)

Homologie: Cow: 100%, Guinea Pig: 90%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CEBPA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CEBPA

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Andere Bezeichnung: CEBPA

Hintergrund:

Background Information: CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

Gene Name: CCAAT/enhancer binding protein (C/EBP), alpha

Alternative Symbols: CEBP, C/EBP-alpha

Protein Name: CCAAT/enhancer-binding protein alpha

Molekulargewicht: 38kDa

Gen-ID: 1050

NCBI Accession: NP_004355

UniProt: P49715

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation