EGR2 Antikörper (C-Term)

Produktnummer ABIN2792631

Es sind 3+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-EGR2 Antikörper wird verwendet zum Nachweis von EGR2 in Proben von Human, Maus, Ratte, Pferd, Schwein, Rind (Kuh), Hund und Kaninchen. Er wurde validiert für WB und IHC.

Kurzübersicht für EGR2 Antikörper (C-Term) (ABIN2792631)

Target: EGR2 (Early Growth Response 2 (EGR2))

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Rind (Kuh), Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-EGR2 Antikörper

Bindungsspezifität: C-Term

Sequenz: PFACDYCGRK FARSDERKRH TKIHLRQKER KSSAPSASVP APSTASCSGG

Kreuzreaktivität: Hund, Human, Maus, Schwein, Ratte (Rattus)

Homologie: Cow: 100%, Dog: 92%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against EGR2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EGR2

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-EGR2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: Human Lung.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 476 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EGR2 Antikörper (ABIN2792631)

Damm, Mylonas, Cosson, Yoshida, Della Valle, Mouly, Diop, Scourzic, Shiraishi, Chiba, Tanaka, Miyano, Kikushige, Davi, Lambert, Gautheret, Merle-Béral, Sutton, Dessen, Solary, Akashi, Vainchenker et al.: "Acquired initiating mutations in early hematopoietic cells of CLL patients. ..." in: Cancer discovery, Vol. 4, Issue 9, pp. 1088-101, (2014) (PubMed).

Lagrange, Martin, Droin, Aucagne, Paggetti, Largeot, Itzykson, Solary, Delva, Bastie: "A role for miR-142-3p in colony-stimulating factor 1-induced monocyte differentiation into macrophages." in: Biochimica et biophysica acta, Vol. 1833, Issue 8, pp. 1936-46, (2013) (PubMed).

Latasa, Ituero, Moran-Gonzalez, Aranda, Cosgaya: "Retinoic acid regulates myelin formation in the peripheral nervous system." in: Glia, Vol. 58, Issue 12, pp. 1451-64, (2010) (PubMed).

Details zu EGR2

Target: EGR2 (Early Growth Response 2 (EGR2))

Andere Bezeichnung: EGR2

Hintergrund: The early growth response protein 2 (EGR2) is a transcription factor with three tandem C2H2-type zinc fingers. Mutations in this gene are associated with the autosomal dominant Charcot-Marie-Tooth disease, type 1.The early growth response protein 2 is a transcription factor with three tandem C2H2-type zinc fingers. Mutations in this gene are associated with the autosomal dominant Charcot-Marie-Tooth disease, type 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMT1D, CMT4E, DKFZp686J1957, FLJ14547, KROX20, AT591
Protein Interaction Partner: RPL7L1, HN1L, RIMKLB, RBM15B, NDUFS2, BPGM, SRA1, DTX1, WWP2, UBC, UBE2I, NAB2, SOX8, MED31, SOX10, HCFC1, ACP5, NFATC1, FASLG,
Protein Size: 476

Molekulargewicht: 50 kDa

Gen-ID: 1959

NCBI Accession: NM_000399, NP_000390

UniProt: P11161